To reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children's Hospital in 2011. This introduction led to a reduction in catheter-related bloodstream infections: 12.7/1000 catheter days before the use of taurolidine, compared with 4.3/1000 catheter days afterwards (n = 7) [relative risk = 0.36, 95% confidence interval: 0.20-0.65 (P = 0.018)].

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Keywords Catheter, Children, Infection, Parenteral nutrition, Taurolidine
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Journal The Pediatric Infectious Disease Journal
Hulshof, E.C. (Emma Claire), Hanff, L.M, Olieman, J.F, De Vette, S. (Susanna), Driessen, G.-J. (Gert-Jan), Meeussen, C.J.H.M, & Escher, J.C. (2017). Taurolidine in pediatric home parenteral nutrition patients. The Pediatric Infectious Disease Journal, 36(2), 233–235. doi:10.1097/INF.0000000000001404