This thesis demonstrates the use of fluorescence-guided therapy in oncology.
First it shows the preclinical validation of two different targets and probes for fluorescence-guided surgery, results that pave the way towards clinical implementation.
Next, the utility of the NIR fluorescence Artemis camera is described.
Lastly, the first steps are made towards fluorescence theranostics in oncology: NIR fluorescence-guided surgery and intra-operative targeted photodynamic therapy.

Additional Metadata
Keywords Fluorescence, fluorescence-guided surgery, photodynamic therapy
Promotor C.W.G.M. Löwik (Clemens) , A.L. Vahrmeijer (Alexander) , S. Keereweer (Stijn)
Publisher Erasmus University Rotterdam
ISBN 978-94-6332-393-2
Persistent URL
Grant This work was funded by the European Commission 7th Framework Programme; grant id h2020/644373 - Preclinical Intra-Operative Image-Guided Surgery and Post-Operative Radiotherapy of Tumours (PRISAR)
van Driel, P.B.A.A. (2018, October 24). Fluorescence-guided Therapy in Oncology : Targeted Imaging and Photodynamic Therapy. Erasmus University Rotterdam. Retrieved from