Hepatitis E, rotavirus and norovirus provoke a substantial disease burden worldwide, both in developed and in developing countries. Hepatitis E virus is the predominant cause of acute hepatitis, while rotavirus and norovirus are the main agents for causing acute gastroenteritis in children. Improved understanding of the disease burden invovled is essential to raise awareness of the importance of the diseases. To achieve better control of these diseases, development of vaccines and novel antiviral therapies will prove exceedingly useful. Viral infections are tightly regulated by many cellular signaling pathways. Dynamic virus-host interactions, including host responses and viral mutations, will determine the outcome of viral infections.

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Keywords Hepatitis E, norovirus, rotavirus, immunity, antiviral
Promotor M.P. Peppelenbosch (Maikel) , Q. Pan (Qiuwei)
Publisher Erasmus University Rotterdam
ISBN 978-94-6375-098-1
Persistent URL hdl.handle.net/1765/110140
Hakim, M.S. (2018, September 12). Hepatic and Enteric Viral Infections: Molecular epidemiology, immunity and antiviral therapy. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/110140