The primary aim of phase I trials is to establish safety profiles. Patients with advanced cancer, without standard treatment options, may struggle to decide whether to engage in a treatment with unknown efficacy, benefit, and side effects, or to opt for symptom-oriented palliative care. In this thesis, both medical outcomes of phase I clinical trials, as well as research towards patients‘ perspectives are presented.

Additional Metadata
Keywords oncology, phase I clinical trials, hope, health related quality of life, patient reported outcomes
Promotor A.H.J. Mathijssen (Ron) , M.J.A. de Jonge (Maja)
Publisher Erasmus University Rotterdam
ISBN 978-94-6299-985-5
Persistent URL
van der Biessen, A.J. (2018, October 31). Hoping for a New Horizon : Phase I oncology clinical trials medical outcomes & patients’ perspectives. Erasmus University Rotterdam. Retrieved from