The primary aim of phase I trials is to establish safety profiles. Patients with advanced cancer, without standard treatment options, may struggle to decide whether to engage in a treatment with unknown efficacy, benefit, and side effects, or to opt for symptom-oriented palliative care. In this thesis, both medical outcomes of phase I clinical trials, as well as research towards patients‘ perspectives are presented.

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A.H.J. Mathijssen (Ron) , M.J.A. de Jonge (Maja)
Erasmus University Rotterdam
Department of Medical Oncology

van der Biessen, D. (2018, October 31). Hoping for a New Horizon : Phase I oncology clinical trials medical outcomes & patients’ perspectives. Retrieved from