2018-04-01
Children and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection
Publication
Publication
Pediatric Blood & Cancer , Volume 65 - Issue 4
Data on management of pediatric marginal zone lymphoma (MZL) are scarce. This retrospective study assessed characteristics and outcome in 66 patients who were <18 years old. Forty-four (67%) had an extranodal MZL (EMZL), 21 (32%) a nodal MZL (NMZL), and one patient a splenic MZL. Thirty-three patients (50%) received a variable combination of adjuvant chemotherapy/immunotherapy/radiotherapy, while the remainder, including 20 of 21 with NMZL, entered an active observation period. Overall survival was excellent (98 ± 2%), although 11 patients relapsed (17%; NMZL, n = 1; EMZL, n = 10), seven after any therapy and four after complete resection only. In conclusion, outcome of NZML, in particular, seems to be excellent after (in)complete resection and observation only.
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| doi.org/10.1002/pbc.26932, hdl.handle.net/1765/112604 | |
| Pediatric Blood & Cancer | |
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Ronceray, L. (Leila), Abla, O., Barzilai-Birenboim, S. (Shlomit), Bomken, S., Chiang, A.K.S. (Alan K. S.), Jazbec, J., … Attarbaschi, A. (2018). Children and adolescents with marginal zone lymphoma have an excellent prognosis with limited chemotherapy or a watch-and-wait strategy after complete resection. Pediatric Blood & Cancer, 65(4). doi:10.1002/pbc.26932 |
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