Neuropsychiatric symptoms (NPS) are increasingly recognized as a core element of Alzheimer's disease (AD); however, clinicians still consider AD primarily as a cognitive disorder. We describe a case in which the underrecognition of NPS as part of AD resulted in substantial delay of an AD diagnosis, a wrong psychiatric diagnosis, and the organization of inappropriate care. The aim of this paper is to acknowledge NPS as an (early) manifestation of AD and to suggest features that may point toward underlying AD in older adults with late-life behavioral changes.

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Journal of Alzheimer's Disease
Department of Neurology

Eikelboom, W.S. (Willem S.), Van Rooij, J.G.J. (Jeroen G. J.), van den Berg, E., Coesmans, M., Jiskoot, L., Singleton, E. (Ellen), … Papma, J. (2018). Neuropsychiatric Symptoms Complicating the Diagnosis of Alzheimer's Disease: A Case Report. Journal of Alzheimer's Disease, 66(4), 1363–1369. doi:10.3233/JAD-180700