Hypereosinophilia encompasses a broad differential diagnosis of atopy/allergic reactions, drug reactions, parasitic infections and paraneoplastic syndromes. Although mostly of limited clinical significance, hypereosinophilia can also be related to hematological malignancies. One has to be aware of the potential for secondary organ damage for example, in the case of hypereosinophilic syndrome. We present three cases with different underlying mechanisms of hypereosinophilia with a brief overview of causes, diagnostic work-up and treatment options.

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hdl.handle.net/1765/113506
The Netherlands Journal of Medicine

van Balkum, M. (M.), Kluin-Nelemans, H. (H.), van Hellemond, J.J, van Genderen, P.J.J, & Wismans, P.J. (2018). Hypereosinophilia: A diagnostic challenge. The Netherlands Journal of Medicine (Vol. 76, pp. 431–436). Retrieved from http://hdl.handle.net/1765/113506