2018-08-01
Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screening
Publication
Publication
Thorax: an international journal of respiratory medicine , Volume 73 - Issue 8
We studied 2240 indeterminate solid nodules (volume 50-500mm 3) to determine the correlation of diameter and semi-automated volume measurements for pulmonary nodule size estimation. Intra-nodular diameter variation, defined as maximum minus minimum diameter through the nodule's center, varied by 2.8 mm (median, IQR:2.2-3.7 mm), so above the 1.5 mm cutoff for nodule growth used in Lung CT Screening Reporting and Data System (Lung-RADS). Using mean or maximum axial diameter to assess nodule volume led to a substantial mean overestimation of nodule volume of 47.2% and 85.1%, respectively, compared to semi-automated volume. Thus, size of indeterminate nodules is poorly represented by diameter. Trial registration number Pre-results, ISRCTN63545820.
| Additional Metadata | |
|---|---|
| , | |
| doi.org/10.1136/thoraxjnl-2017-210770, hdl.handle.net/1765/114248 | |
| Thorax: an international journal of respiratory medicine | |
| Organisation | Department of Public Health |
|
Heuvelmans, M., Walter, J.E. (Joan E), Vliegenthart, R., van Ooijen, P., de Bock, G., De Koning, H.J. (Harry J.), & Oudkerk, M. (2018). Disagreement of diameter and volume measurements for pulmonary nodule size estimation in CT lung cancer screening. Thorax: an international journal of respiratory medicine, 73(8). doi:10.1136/thoraxjnl-2017-210770 |
|