Background: Seborrhoeic dermatitis is a chronic relapsing inflammatory skin disease with unclear pathophysiological mechanisms. Objectives: To establish which lifestyle and physiological determinants are associated with seborrhoeic dermatitis. Methods: Seborrhoeic dermatitis was diagnosed by a trained physician during a full-body skin examination within the Rotterdam Study, a prospective population-based cohort study in middle-aged and elderly people. The current design is a comparative cross-sectional study embedded in the Rotterdam Study. Potential factors were identified from the literature and analysed in a multivariable logistic regression, including: age, sex, obesity, skin colour, stress, depression, education level, hypertension, climate, xerosis cutis, alcohol and tobacco use. Results: Of the 5498 participants, 788 participants were diagnosed with seborrhoeic dermatitis (14·3%). We found associations between seborrhoeic dermatitis and male sex [adjusted odds ratio (OR) 2·09, 95% confidence interval (CI) 1·77–2·47], darker skin (adjusted OR 0·39, 95% CI 0·22–0·69), season (summer vs. winter: adjusted OR 0·63, 95% CI 0·48–0·82) and generalized xerosis cutis (adjusted OR 1·41, 95% CI 1·11–1·80). Conclusions: Seborrhoeic dermatitis is one of the most common inflammatory dermatoses in middle-aged and elderly individuals, especially during winter. Men, and people with a light and dry skin were most likely to have seborrhoeic dermatitis.

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Journal British Journal of Dermatology
Sanders, M.G.H. (M. G.H.), Pardo Cortes, L.M, Franco, O.H, Ginger, R.S. (R. S.), & Nijsten, T.E.C. (2018). Prevalence and determinants of seborrhoeic dermatitis in a middle-aged and elderly population: the Rotterdam Study. British Journal of Dermatology, 178(1), 148–153. doi:10.1111/bjd.15908