Previous reports suggest that radiation therapy for breast cancer can cause ischemic heart disease, with radiationrelated risk increasing linearly with mean whole heart dose. This study aimed to validate these findings and assesses additional risk factors for radiation-related myocardial infarction in a case-control study nested within a cohort of BC survivors treated 70 years of age during 1970-2009. The study confirms a linear relationship between mean whole heart dose and myocardial infarction risk after radiation for breast cancer.

Additional Metadata
Persistent URL dx.doi.org/10.1016/j.ijrobp.2018.10.025, hdl.handle.net/1765/115224
Journal International Journal of Radiation: Oncology - Biology - Physics
Citation
J.N. Jacobse (Judy), F.K. Duane (Frances), N.B. Boekel (Naomi), Schaapveld, M, Hauptmann, M, Hooning, M.J, … Taylor, C.W. (2019). Radiation Dose-Response for Risk of Myocardial Infarction in Breast Cancer Survivors. International Journal of Radiation: Oncology - Biology - Physics, 103(3), 595–604. doi:10.1016/j.ijrobp.2018.10.025