2019-03-20
External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort
Publication
Publication
Hypertension in Pregnancy , Volume 38 - Issue 2 p. 78- 88
Objective: To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods: Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results: 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion: Only a few easily applicable prognostic models for all PE showed discrimination above 0.70, which is considered an acceptable performance.
| Additional Metadata | |
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| , , , | |
| doi.org/10.1080/10641955.2019.1584210, hdl.handle.net/1765/116213 | |
| Hypertension in Pregnancy | |
| Organisation | Rheumatology |
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de Ruiter, M., Kwee, A., Naaktgeboren, CA, Louhanepessy, R.D., de Groot, I., Evers, IM, … Koster, M.P.H. (2019). External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort. Hypertension in Pregnancy, 38(2), 78–88. doi:10.1080/10641955.2019.1584210 |
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