We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

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Persistent URL dx.doi.org/10.1117/12.2506151, hdl.handle.net/1765/117758
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Wang, T, Pfeiffer, A.F.H, Daemen, J, Mastik, F, Wieser, W, van der Steen, A.F.W, … van Soest, G. (2019). Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. doi:10.1117/12.2506151