Peripartum cardiomyopathy (PPCM) is a rare form of pregnancy-associated heart failure and is considered to be a diagnosis of exclusion. There are many hypotheses on the aetiology of PPCM; however, the exact pathophysiological mechanism remains unknown. It shows many resemblances to other conditions, such as familial dilated cardiomyopathy or myocarditis, and therefore it can be hard to make a definite diagnosis.

We describe four cases of peripartum-onset heart failure in women who were suspected of having PPCM. We discuss the differential diagnosis, pathophysiological mechanisms and various diagnostic modalities.

Additional Metadata
Persistent URL,
Journal Heart
Baris, L, Cornette, J.M.J, Johnson, M.R, Sliwa, K, & Roos-Hesselink, J.W. (2019). Peripartum cardiomyopathy: disease or syndrome?. Heart, 105(5), 357–362. doi:10.1136/heartjnl-2018-314252