Signal transducer and activator of transcription molecules (STATs) are messenger molecules that play a very important role in the function of cells. Dysfunction of these STATs leads to an immunodeficiency disorder and/or autoimmunity. This was studied in detail in the dissertation on the basis of patients with a genetic mutation in the STAT1 and STAT3 gene.

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P.M. van Hagen (Martin) , V.A.S.H. Dalm (Virgil) , W.A. Dik (Willem)
Erasmus University Rotterdam
hdl.handle.net/1765/119359
Department of Immunology

Meesilpavikkai, K. (2019, October 9). The State of STATs in Primary Immunodeficiencies : Molecular Diversity and Implications for Therapy. Retrieved from http://hdl.handle.net/1765/119359