The general aim of this thesis is to investigate two themes relevant to adolescent and young adult IBD patients: psychosocial problems, especially anxiety and depression, and transition to adult care.
The specific aims of this thesis are:
- To systematically review the scientific international literature with regard to the prevalence of anxiety and/or depression in paediatric and adolescent IBD
- To study the prevalence and risk factors of anxiety and/or depression in Dutch adolescents and young adult patients with IBD
- To investigate the effectiveness of cognitive behavioural therapy on both psychological symptoms and clinical disease course in young IBD patients suffering from mild or subclinical anxiety and/or depressive symptoms
- To identify immunological profiles in IBD patients with anxiety and/or depression, and investigate if these profiles are altered by cognitive behavioural therapy
- To study outcome of transition, especially identifying which factors health care providers and patients find important for success of transition to adult care.

Additional Metadata
Keywords IBD, Ziekte van Crohn, Colitis Ulcerosa, transitie transfer, angst, depressie, psychotherapie, cognitieve gedragstherapie, ziektebeloop
Promotor J.C. Escher (Johanna) , E.M.W.J. Utens (Elisabeth)
Publisher Erasmus University Rotterdam
Sponsor Main financial support for this project was kindly given by Stichting Crohn en Colitis Ulcerosa Fonds Nederland / Maag Lever Darm St´╗┐ichting, Fonds NutsOhra, Stichting Theia, and Stichting Vrienden van het Sophia.
ISBN 978-94-6380-421-9
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
van den Brink, G. (2019, September 17). Improving care for young IBD patients : Psychosocial and clinical factors. Erasmus University Rotterdam. Retrieved from