Purpose This report describes the development and validation process of an assessment with national consensus in appropriate and safe pharmacotherapy. Methods A question-database on safe prescription based on literature of pharmacotherapy-related harm was developed by an expert group from Dutch medical faculties. Final-year medical students concluded a 2-year education program on appropriate and safe prescription by one of nine assessment variants of 40 multiple-choice questions each. An expert panel of professionals (n = 10) answered all database questions and rated questions on relevance. Questions were selected for revision based on lack of relevance or poor test and item characteristics. Results A total of 576 final-year medical students of the Radboud University was assessed. There was no significant difference in performance between students and content expert group (p = 0.7), probably due to learning behavior. Out of 165 questions, 59 were selected for revision. Conclusion Joint national effort from a team of experts in prescription and pharmacotherapy is an appropriate way to achieve a valid and reliable last-year student drug prescription assessment.

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Keywords Prescribing . Medication safety . Education
Persistent URL dx.doi.org/10.1007/s00228-019-02686-1, hdl.handle.net/1765/119453
Journal European Journal of Clinical Pharmacology
Jansen, D.R.M., Keijsers, C., Kornelissen, M.O., Rikkert, M., Kramers, C, Tichelaar, J, … Knol, W. (2019). Towards a "prescribing license" for medical students: development and quality evaluation of an assessment for safe prescribing. European Journal of Clinical Pharmacology, 75(9), 1261–1268. doi:10.1007/s00228-019-02686-1