Loss of normal bowel control has a devastating effect on quality of life. Psychological implications and social restrictions with impaired continence have been extensively documented. Therefore restoration of intestinal continuity after rectal resection with acceptable postoperative morbidity is a challenge to surgeons. This thesis will focus on the functional outcome after sphincter-preserving procedures in the treatment of ulcerative colitis and rectal cancer. Especially, continence mechanisms after colonic pouch construction and the role of gut flora in the etiology of pouchitis after ileal pouch surgery have been investigated.

Benner, Prof. Dr. R. (promotor), Tilanus, Prof. Dr. H.W. (promotor), B-K Medical, the Campina Institute, Coloplast BV, ConvaTec BV, Covidien Nederland BV, EuroTec BV, Johnson & Johnson Medical BV, Hoogland Medical BV, Nationaal Fonds tegen Kanker, Sanofi-Aventis Netherlands BV, Tramedico Yakult Nederland BV, CombiCare BV, ERBE Benelux BV, Norgine BV, Nycomed BV.
Erasmus MC: University Medical Center Rotterdam
R. Benner (Robbert) , H.W. Tilanus (Hugo)
Erasmus MC: University Medical Center Rotterdam

Gosselink, M. P. (2008, April 2). Functional outcome after pouch surgery in patients with ulcerative colitis or rectal cancer. Retrieved from http://hdl.handle.net/1765/11974