Aims of the thesis
1. To review the recently identified roles of NCC in the regulation of sodium, potassium, and blood pressure (Chapter 2)
2. To analyze the regulation of NCC during potassium-induced natriuresis (Chapter 3)
3. To review the role of pharmacogenetics in CNI-induced hypertension (Chapter 4)
4. To test the anti-hypertensive effects of thiazide diuretics in hypertensive kidney transplant recipients using tacrolimus (Chapter 5)
5. To analyze the effects of CNIs on NCC in uEVs (Chapter 6)
6. To identify the mechanism of the anti-hypertensive effect of MMF in experimental hypertension (Chapter 7)
7. To analyze the relationship between calcineurin inhibitors, serum magnesium, and posttransplantation diabetes mellitus (Chapter 8)

Additional Metadata
Promotor E.J. Hoorn (Ewout) , R. Zietse (Bob)
Publisher Erasmus University Rotterdam
ISBN 978-94-6361-323-1
Persistent URL
Moes, A.D. (2019, October). Effects of Immunosuppressive Drugs on Blood Pressure and Electrolyte Homeostasis. Erasmus University Rotterdam. Retrieved from