2019
Active Nano-targeting of Macrophages
Publication
Publication
Current pharmaceutical design , Volume 25 - Issue 17 p. 1951- 1961
Macrophages play a role in almost every disease such as cancer, infections, injuries, metabolic and inflammatory diseases and are becoming an attractive therapeutic target. However, understanding macrophage diversity, tissue distribution and plasticity will help in defining precise targeting strategies and effective therapies. Active targeting of macrophages using nanoparticles for therapeutic purposes is still at its infancy but holds promises since macrophages have shown high specific uptake of nanoparticles. Here, we highlight recent progress in active nanotechnology-based systems gaining pivotal roles to target diverse macrophage subsets in diseased tissues.
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doi.org/10.2174/1381612825666190710114108, hdl.handle.net/1765/120035 | |
Current pharmaceutical design | |
Organisation | Department of Radiology |
Gaspar, N. (Natasa), Zambito, G. (Giorgia), Löwik, C.M.W.G. (Clemens M W G), & Mezzanotte, L. (2019). Active Nano-targeting of Macrophages. Current pharmaceutical design, 25(17), 1951–1961. doi:10.2174/1381612825666190710114108 |