In this thesis we describe studies that aim to unravel the role of B-cell intrinsic factors (such as B cell receptor signaling) and extrinsic factors (such as signaling induced by CD40L, which is expressed on activated T cells) in the pathogenesis of the chronic lymphocytic leukemia.

Additional Metadata
Promotor R.W. Hendriks (Rudi) , A.W. Langerak (Anton)
Publisher Erasmus University Rotterdam
Sponsor The studies were financially supported by the Post graduate school Molecular Medicine, the Dutch Cancer Society and the Departments of Pulmonary Medicine and Immunology, Erasmus MC Rotterdam
ISBN 978-94-91811-22-7
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
Singh, S.P. (2019, October 29). Signal Transduction Pathways in Chronic Lymphocytic Leukemia. Erasmus University Rotterdam. Retrieved from