The immune system in the intestine has to adapt to a constantly changing mucosal environment. A dynamic balance between regulatory and inflammatory immune cells determines the outcome between intestinal health and disease. In search for new parameters to classify patients with inflammatory bowel disease (IBD), this thesis investigates the underlying immune mechanisms that establish and maintain this balance.

Additional Metadata
Keywords Immunology, intestinal immune system, inflammatory bowel disease, T-cell mediated inflammatory disease, T cells
Promotor J.C. Escher (Johanna) , J.N. Samsom (Janneke)
Publisher Erasmus University Rotterdam
Sponsor The research described in this thesis was supported by the Netherlands Organisation for Scientific Research (Grant 2013/09420/BOO) and The Dutch Sophia Research Foundation (Grants S13-19, S13-671 and S14-17). The European Crohn’s and Colitis Organisation and CrocoKids financially supported experimental costs.
ISBN 978-94-6361-324-8
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
Joosse, M.E. (2019, November 6). A Dynamic Balance: Regulatory and inflammatory T-cell responses in inflammatory bowel disease. Erasmus University Rotterdam. Retrieved from