Acute withdrawal of calcium channel blockers can lead to the so-called calcium channel blocker withdrawal phenomenon, in particular, when high dosages are used. In the case presented, inadequate drug substitution led to this phenomenon which resulted in a serious course of events. Careful monitoring the process of drug substitution with respect to equal therapeutic dosages is therefore a necessity, especially in vulnerable patients.

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Keywords Angina pectoris, calcium channel blockers, denervation, humans, nitrates
Persistent URL
Journal The Netherlands Journal of Medicine
Peeters, L.E.J, den Uil, C.A, Feyz, L, van den Bemt, P.M.L.A, Daemen, J. (J.), & Versmissen, J. (2019). Acute calcium channel blocker withdrawal-induced cardiac arrest. The Netherlands Journal of Medicine, 77(9), 341–343. Retrieved from