In this paper, we present a planning and control framework for manufacture-to-order environments that enables and supports agile-based discrete parts manufacturing. The characteristic elements of our framework are that it is decentralized, logistics and business oriented, and that it recognizes that more detailed and more reliable data become available as orders advance through the different manufacturing stages and departments. Furthermore, it is a generic framework in that it applies to any discrete parts manufacturer, ranging from an engineer-to-order to an assemble-to-order company. We also point out the necessity of an organizational structure that supports and reinforces the framework. Particularly, we discuss the adoption and implementation of the new framework by creating multi-disciplinary teams and structural and operational supporting groups to strengthen the organization for agile manufacturing.