This thesis focuses on the natural history, risk stratification, and treatment of patients with primary biliary cholangitis. The aims of this thesis were to assess:
1. the predictive value of bilirubin within the normal range on transplant-free survival among patients with PBC
2. the incidence of and risk factors for cirrhosis-related complications among ursodeoxycholicacid treated patients with PBC
3. the association between ursodeoxycholic acid and transplant-free survival in patients with PBC, both in relative and absolute measures
4. biochemical response and clinical outcome of PBC patients treated with fenofibrate and bezafibrate
5. the estimated survival benefit induced by treatment with obeticholic acid in patients with PBC
6. time trends in liver transplantation for patients with PBC.

H.J. Metselaar (Herold) , H.R. van Buuren (Henk) , B.E. Hansen (Bettina)
Erasmus University Rotterdam
hdl.handle.net/1765/124059
Department of Gastroenterology & Hepatology

Harms, M. (2020, January 10). Prognosis and Treatment of Primary Biliary Cholangitis : a new name – a new era. Retrieved from http://hdl.handle.net/1765/124059