This thesis focuses on the natural history, risk stratification, and treatment of patients with primary biliary cholangitis. The aims of this thesis were to assess:
1. the predictive value of bilirubin within the normal range on transplant-free survival among patients with PBC
2. the incidence of and risk factors for cirrhosis-related complications among ursodeoxycholicacid treated patients with PBC
3. the association between ursodeoxycholic acid and transplant-free survival in patients with PBC, both in relative and absolute measures
4. biochemical response and clinical outcome of PBC patients treated with fenofibrate and bezafibrate
5. the estimated survival benefit induced by treatment with obeticholic acid in patients with PBC
6. time trends in liver transplantation for patients with PBC.

Additional Metadata
Promotor H.J. Metselaar (Herold) , H.R. van Buuren (Henk) , B.E. Hansen (Bettina)
Publisher Erasmus University Rotterdam
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
Harms, M.H. (2020, January 10). Prognosis and Treatment of Primary Biliary Cholangitis : a new name – a new era. Erasmus University Rotterdam. Retrieved from