An insulinoma is a neuroendocrine tumor of the pancreas, arising from the β-cell, resulting in endogenous hyperinsulinemia. This causes hypoglycemia with neurogycopenic symptoms. Diagnosis of insulinoma starts with demonstrating elevated insulin during a spontaneous hypoglycemia or a hypoglycemia can be provoked by a 72-h fasting test. Most insulinomas are benign and localized to the pancreas and can be surgically resected. Rare metastastic insulinomas are treated with diazoxide or somatostatin analogues.

, , ,
doi.org/10.1016/B978-0-12-801238-3.65228-5, hdl.handle.net/1765/124752
Erasmus MC: University Medical Center Rotterdam

Zandee, W., & de Herder, W. (2018). Insulinoma. In Encyclopedia of Endocrine Diseases (pp. 58–62). doi:10.1016/B978-0-12-801238-3.65228-5