Reducing radiation exposure in second-generation cryoballoon ablation without compromising clinical outcome
Purpose: Pulmonary vein isolation (PVI) using cryoballoon (CB) ablation is associated with an increased radiation exposure compared with radiofrequency ablation. Previous studies showed that radiation exposure in CB PVI can be reduced by optimizing the fluoroscopy protocol without comprising acute efficacy and safety. We evaluated the mid-term outcome of a modified fluoroscopy protocol in patients undergoing CB PVI. Methods: The study population comprised 90 consecutive patients who underwent second-generation CB-based PVI. The first 46 patients underwent CB PVI with conventional fluoroscopy settings (group A, historic control group). In the following 44 patients (group B), a modified fluoroscopy protocol was applied consisting of (1) visualization of degree of PV occlusion only by fluoroscopy (no cine runs); (2) increased radiation awareness. Primary endpoints were the total dose area product (DAP), fluoroscopy time, and freedom from documented recurrence of atrial fibrillation (AF) after a single procedure. Results: Group B had a lower median DAP (1393 cGycm2 vs. 3232 cGycm2, P < 0.001) and median fluoroscopy time (20 min vs. 24 min, P < 0.001) as compared with group A. The 1-year freedom from documented recurrence of AF after a single procedure was similar among groups (74% in group A vs. 77% in group B, P = 0.71). There were no significant differences between both groups for the secondary endpoints, including procedure duration, proportion of patients with complete electrical isolation, and complications. Conclusion: Using a modified fluoroscopy protocol and increased radiation awareness, radiation exposure can be significantly reduced in CB PVI with a similar 1-year clinical outcome.
|Keywords||Atrial fibrillation, Cryoballoon ablation, Fluoroscopy, Pulmonary vein isolation, Radiation exposure|
|Persistent URL||dx.doi.org/10.1007/s10840-020-00737-7, hdl.handle.net/1765/126536|
|Journal||Journal of Interventional Cardiac Electrophysiology|
Holl, M.J, Bhagwandien, R.E, Firouzi, M. (Mehran), de Ruiter, W.A. (Wouter A.), Szili-Török, T, & Yap, S-C. (2020). Reducing radiation exposure in second-generation cryoballoon ablation without compromising clinical outcome. Journal of Interventional Cardiac Electrophysiology. doi:10.1007/s10840-020-00737-7