A human monoclonal antibody blocking SARS-CoV-2 infection

Wang, Chunyan; Li, Wentao; Drabek, Dubravka; Okba, Nisreen; van Haperen, Rien; Osterhaus, Albert; van Kuppeveld, Frank; Haagmans, Bart; Grosveld, Frank; Bosch, Berend Jan

doi:10.1038/s41467-020-16256-y

Wang, C. (Chunyan), Li, W. (Wentao), D.D. Drabek (Dubravka), N.M.A. Okba (Nisreen), M.J. van Haperen (Rien), A.D.M.E. Osterhaus (Albert), F.J.M. van Kuppeveld (Frank ), B.L. Haagmans (Bart), F.G. Grosveld (Frank) and B.J. Bosch (Berend Jan)

2020-05-04

A human monoclonal antibody blocking SARS-CoV-2 infection

Nature Communications , Volume 11 - Issue 1

The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.

Additional Metadata
Persistent URL	doi.org/10.1038/s41467-020-16256-y, hdl.handle.net/1765/126755
Journal	Nature Communications
Organisation	Biophysical Genomics, Department Cell Biology & Genetics
Citation APA Style AAA Style APA Style Cell Style Chicago Style Harvard Style IEEE Style MLA Style Nature Style Vancouver Style American-Institute-of-Physics Style Council-of-Science-Editors Style BibTex Format Endnote Format RIS Format CSL Format DOIs only Format	Wang, C. (Chunyan), Li, W. (Wentao), Drabek, D., Okba, N., van Haperen, R., Osterhaus, A., … Bosch, B. J. (2020). A human monoclonal antibody blocking SARS-CoV-2 infection. Nature Communications, 11(1). doi:10.1038/s41467-020-16256-y

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