Introduction: Many studies have investigated the impact of orthodontic treatment need (OTN) on children's oral health–related quality of life (OHRQOL). However, few studies have explored the impact of deviant occlusal traits on OHRQOL regarding the severity of OTN. This cross-sectional study aims to address this gap in the literature. Methods: This study was conducted within the Generation R Study, a population-based prospective cohort study. We assessed OTN with the Index of Orthodontic Treatment Need and OHRQOL with a parental short-form of the Child Oral Health Impact Profile in 3048 children at a median age of 9.74 years (9.5-10.0). We also further assessed individual malocclusion traits in a subsample of 2714 children. We investigated the association between OTN, malocclusion traits, and OHRQOL using multiple regression analysis with weighted least squares. Results: Children with definite (adjusted effect estimate = −0.81; 95% confidence interval −1.12 to −0.50) or borderline (adjusted effect estimate = −0.34; 95% confidence interval −0.61 to −0.08) OTN experienced significant decreases in their OHRQOL than those with no need. An impacted tooth, increased overjet, or crowding had significant negative impacts on children's OHRQOL. Children with an overjet experienced negative impacts on OHRQOL even when orthodontic treatment was not necessary. Conclusions: Progressively greater OTN has increasingly negative impacts on parent's perception of children's OHRQOL. In particular, children presenting with large overjets and impacted teeth have lower OHRQOL. These perspectives add to better patient-clinician communication and understanding of patient expectations around OTN, which may potentially lead to improvements in quality of care from the patient perspective.,
American Journal of Orthodontics and Dentofacial Orthopedics
Generation R Study Group

Nguee, A.-M.A.M. (Amanda-mae A.M.), Ongkosuwito, E.M, Jaddoe, V.W.V, Wolvius, E.B, & Kragt, L. (2020). Impact of orthodontic treatment need and deviant occlusal traits on oral health–related quality of life in children: A cross-sectional study in the Generation R cohort. American Journal of Orthodontics and Dentofacial Orthopedics, 157(6), 764–772.e4. doi:10.1016/j.ajodo.2019.06.015