The association between patellar tendon stiffness measured with shear-wave elastography and patellar tendinopathy—a case-control study
Objectives: (1) To determine the association between patellar tendon stiffness and the presence of patellar tendinopathy (PT). (2) To evaluate the reliability of shear-wave elastography (SWE). Methods: Participants were consecutively enrolled between January 2017 and June 2019. PT was diagnosed clinically and confirmed by either grayscale US or power Doppler US, or both. Controls had no history of anterior knee pain and no clinical signs of PT. Patellar tendon stiffness (kilopascal, kPa) was assessed using SWE. Logistic regression was used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Reliability analyses included coefficients-of-variation (CV), coefficients-of-repeatability (CR), intraclass correlation coefficient (ICC) for intraobserver and interobserver reliability, and Bland-Altman analysis. Results: In total, 76 participants with PT (58 men, mean age 24.4 ± 3.8 years) and 35 asymptomatic controls (16 men, mean age 21.5 ± 3.8 years) were included. Univariate analyses (OR 1.094, 95% CI 1.061–1.128, p <.001) and adjusted multivariate analyses (OR 1.294, 95% CI 1.044–1.605, p =.018) showed that athletes with PT had significantly increased patellar tendon stiffness. ICC for intraobserver reliability was 0.95 (95% CI 0.92–0.97), CR (CV) 12 kPa (10%) and 0.79 (95% CI 0.65–0.88), CR (CV) 18 kPa (21%) for interobserver reliability. Mean differences from Bland-Altman analysis were 5.6 kPa (95% CI 3.1–8.1, p <.001) for intraobserver reliability and 4.6 kPa (95% CI 1.9–7.2, p <.001) for interobserver reliability. Conclusions: PT is associated with significantly higher patellar tendon stiffness. SWE measurements demonstrate excellent intraobserver reliability and good interobserver reliability. Therefore, SWE is a promising tool to implement in longitudinal studies and future studies should evaluate its prognostic value and utility as a monitoring tool in athletes with PT. Key Points: • Patellar tendon stiffness measured with shear-wave elastography (SWE) is higher in athletes with patellar tendinopathy than in healthy controls, also after adjusting for potential confounders. • Excellent intraobserver reliability and good interobserver reliability were found for the quantitative assessment of patellar tendon stiffness using SWE.
|Keywords||Athletes, Elasticity imaging techniques, Patellar ligament, Reproducibility of results, Tendinopathy|
|Persistent URL||dx.doi.org/10.1007/s00330-020-06952-0, hdl.handle.net/1765/127769|
|Journal||European Radiology: journal of the European Congress of Radiology|
Breda, S.J, van der Vlist, A. (Arco), de Vos, R.J, Krestin, G.P, & Oei, E.H.G. (2020). The association between patellar tendon stiffness measured with shear-wave elastography and patellar tendinopathy—a case-control study. European Radiology: journal of the European Congress of Radiology. doi:10.1007/s00330-020-06952-0