In this thesis, I describe the results of my research into the clinical utility of existing risk calculators and their updates.
I also discuss the effect of the underlying patient risk of low to high ranging prostate cancer, and the life expectancy of the case in question, focusing on middle-aged and elderly males.

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M.J. Roobol-Bouts (Monique)
E.W. Steyerberg (Ewout)
Erasmus University Rotterdam
Department of Urology