In this thesis I have examined structural and functional brain changes in (presymptomatic) familial frontotemporal dementia, using MRI. Results point towards genotypic patterns and trajectories of brain change, which is important for diagnostic considerations, but also warrants the correct use of MRI based biomarkers in pharmaceutical trials.

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Keywords MRI, frontotemporal dementia, longitudinal, neuroimaging
Promotor J.C. van Swieten (John) , S.A.R.B. Rombouts (Serge) , J.M. Papma (Janne)
Publisher Erasmus University Rotterdam
Sponsor The research projects described in this thesis have been supported by The Netherlands Organization for Scientific Research (NWO), ZonMW Memorabel, the Association for Frontotemporal Dementia Research, the Dioraphte Foundation, Alzheimer Nederland, and the Bluefield Project
ISBN 978-94-6380-880-4
Persistent URL
Note For copyright reasons there is a partial embargo for this dissertation
Panman, J.L. (2020, September 11). Neuroimaging Trajectories in Presymptomatic Frontotemporal Dementia. Erasmus University Rotterdam. Retrieved from