Influence of (Co-)Medication on Haemostatic Biomarkers
De invloed van (co-)medicatie op biomarkers van de stolling
We showed that the simplified diagnostic YEARS algorithm for suspected acute pulmonary embolism can be safely applied in patients presenting in the hospital, also in patients using statins or antiplatelet drugs, but that the diagnosis of VTE in schizophrenic patients remains difficult.
Additionally, we showed that statins but not antiplatelet drugs and PCSK9 inhibitors influence D-dimer levels and that in participants with prior VTE, statin use led to an improved breakdown of blood clots compared to non-statin use.
|Keywords||Venous Thromboembolism, Pulmonary Embolism, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Diagnostic tests, Platelet Aggregation Inhibitors, Fibrinolysis, fibrin fragment D, D-dimer PCSK9 inhibitor|
|Promotor||T. van Gelder (Teun) , M.J.H.A. Kruip (Marieke) , J. Versmissen (Jorie)|
|Publisher||Erasmus University Rotterdam|
|Organisation||Department of Pharmacy|
Schol-Gelok, S. (2020, September 23). Influence of (Co-)Medication on Haemostatic Biomarkers. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/129599