Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands
Aim: We assessed the association between ethnicity and the risk of gestational diabetes mellitus (GDM) in the Netherlands. Methods: A cohort of 7815 women with known GDM status and ethnicity, including women of Sub-Saharan African ethnicity who are currently not identified as high-risk in guidelines. We compared GDM rates among participants of ethnicity to those of ethnic Dutch participants. We employed multivariable regression to correct for possible confounders, including maternal age, pre-pregnancy body mass index (BMI), and education. GDM prevalence and odds ratios based on ethnicity were the main outcome measures. Results: The prevalence rates of GDM according to ethnicity were: Dutch 0.6%, South-Asian Surinamese 6.9%, African-Surinamese 3.5%, Antillean 1.0%, Turkish 1.0%, Moroccan 1.4%, Ghanaian 6.8%, Sub-Saharan African 3.5%, other Western 0.5% and other non-Western 2.8%. After adjustment for age, pre-pregnancy BMI, and education duration, compared with the reference Dutch-ethnicity population, adjusted odds ratios (aOR) for GDM were statistically significantly higher in South-Asian Surinamese (aOR 10.9; 95% Confidence Interval (CI), 4.7–25.0), African-Surinamese (4.3; 2.0–9.2), Ghanaian (6.5; 3.0–14.5), Sub-Saharan African (5.7; 2.0–16.0), and other non-Western women (4.5; 2.2–9.0). GDM was not significantly increased among Antillean (1.4; 0.2–10.3), Turkish (1.4; 0.4–4.2), Moroccan (1.8; 0.8–4.0), and other Western women (0.8; 0.3–2.2). Conclusions: This study shows for the first time in the Netherlands that women of Ghanaian or other Sub-Saharan African ethnicity have an increased risk of developing GDM than the Dutch. This calls for adaptation of the Dutch guidelines of screening high-risk groups for GDM and more awareness amongst obstetric caregivers.
|Keywords||Ethnicity, Gestational diabetes mellitus, Pregnancy, Risk-factors|
|Persistent URL||dx.doi.org/10.1016/j.diabres.2020.108367, hdl.handle.net/1765/130012|
|Journal||Diabetes Research and Clinical Practice|
Rademaker, D. (D.), van Schaijik, C.I. (C. I.), Oostvogels, A.J.J.M. (A. J.J.M.), van Rijn, B.B, Evers, I. (I.), Devries, J.H, … Painter, R.C. (2020). Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands. Diabetes Research and Clinical Practice, 168. doi:10.1016/j.diabres.2020.108367