Porphyrias are rare metabolic disorders. Lack of awareness and knowledge about the clinical features of porphyrias results in diagnostic and therapeutic delays for many patients. Delays in diagnosing and treating porphyrias can result in severe, progressive morbidity (and mortality) and psychological distress for patients. This review discusses the pathophysiology, diagnosis, treatment, and follow-up of the most prevalent porphyrias: acute intermittent porphyria, porphyria cutanea tarda, and erythropoietic protoporphyria.

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Keywords Acute intermittent porphyria, diagnosis, erythropoietic porphyria, porphyria cutanea tarda, porphyrias
Persistent URL hdl.handle.net/1765/130233
Journal The Netherlands Journal of Medicine
Citation
Neeleman, R.A., Wensink, D., Wagenmakers, M., Mijnhout, G.S., Friesema, E.C.H, & Langendonk, J.G. (2020). Diagnostic and therapeutic strategies for porphyrias. The Netherlands Journal of Medicine, 78(4), 149–160. Retrieved from http://hdl.handle.net/1765/130233