The publication in January 2001 of the first-in-man results showing zero restenosis after sirolimus-eluting stent implantation produced enormous excitement in the cardiological community. The long-awaited tool—a safe, restenosis-proof, easy-to-use stent— had been found. It was not too long thereafter that paclitaxel-eluting stents also demonstrated their capability to decrease restenosis.

Blood Vessel Prosthesis Implantation/adverse effects/statistics & numerical data, Clinical Trials/statistics & numerical data, Coronary Restenosis/prevention & control, Cost-Benefit Analysis/*statistics & numerical data, Drug Implants/adverse effects/*economics/therapeutic use, Humans, Stents/adverse effects/*economics/statistics & numerical data, Treatment Outcome,
Circulation (Baltimore)
Erasmus MC: University Medical Center Rotterdam

Lemos Neto, P.A, Serruys, P.W.J.C, & Sousa, J.E. (2003). Drug-eluting stents: cost versus clinical benefit. Circulation (Baltimore), 107(24), 3003–3007. doi:10.1161/01.CIR.0000078025.19258.28