Carcinogenesis, Prediction, and Palliative Treatment of Gastrointestinal Cancer
Carcinogenese, predictie en palliatieve behandeling van gastro-intestinale carcinomen
The aim of this thesis was to gain better understanding of the etiology, the detection, and the palliative treatment of gastrointestinal cancer. We found HOX genes are mediators of (pre)malignant gastrointestinal lesions, vitamin D receptor polymorphisms and immunohistochemical biomarkers can be used to predict the risk of esophageal adenocarcinoma development, and palliative therapy modestly prolongs patient’s life and cost effectiveness of therapies can be assessed after phase II trials.
|M.P. Peppelenbosch (Maikel) , M.J. Bruno (Marco) , M.C.W. Spaander (Manon) , G.M. Fuhler (Gwenny)|
|Erasmus University Rotterdam|
|Organisation||Department of Gastroenterology & Hepatology|
Janmaat, V.T. (2020, October 27). Carcinogenesis, Prediction, and Palliative Treatment of Gastrointestinal Cancer. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/134645