At this moment, for over 60 drugs have been shown to cause QTc prolongation, which is a serious risk factor for ventricular arrhythmias and sudden cardiac death. The risk might increase when such drugs are combined. However, the exact magnitude of the problem is unknown making it difficult for health care professionals to interpret these drug-drug interactions. Therefore, the aim of this PhD project is to provide guidance on safe prescription practices by gaining more insight into the prevalence and associated risk factors of QT prolongation in patients using QTc-prolonging drugs.

QTc-prolongation, Drug-drug interactions, Risk management, Prediction model, Torsade des Pointes, QTc-verlenging, Geneesmiddelinteracties, Risico management, Predictie model
T. van Gelder (Teun) , P.M.L.A. van den Bemt (Patricia)
Erasmus University Rotterdam
978-94-93197-56-5
hdl.handle.net/1765/135410

Berger, F.A. (2021, April 28). Drug induced QTc-prolongation: Towards a better understanding of potential risks. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/135410