The subject of this thesis is the role of rare genetic variation in the etiology of psychiatric disorders. The studies included in this work include a human genetics study on depression, a disease-modeling study for autism spectrum disorder using brain organoids, and the generation of an in vitro cellular drug-screening platform for schizophrenia. The research participants in these studies come from the genetically isolated Amish and Mennonite populations.

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S.A. Kushner (Steven)
Erasmus University Rotterdam

de Jong, J. (2021, September 28). Discovery and Neurobiological Modeling of Rare Genetic Variant Risk for Mental Illness. Retrieved from