<p>Objective: We evaluated whether patient-reported outcome trajectories (i.e., changes over time) differed by intraoperative compartmental cartilage lesion pattern over 4–6 years following arthroscopic meniscal surgery. Methods: In this ancillary study of the Knee Arthroscopy Cohort Southern Denmark cohort, we intraoperatively categorized cartilage lesions as isolated patellofemoral, isolated tibiofemoral, or combined patellofemoral/tibiofemoral. Participants completed the Knee injury and Osteoarthritis Outcome Score (KOOS) pre-operatively, at 3 and 12 months, and at 4–6 years post-operatively and reported overall satisfaction at final follow-up. Our main outcome was KOOS<sub>4</sub> (grand mean of four subscale means). We evaluated whether KOOS<sub>4</sub> scores changed over time according to cartilage lesion patterns using adjusted mixed linear regression. We also estimated probability of treatment satisfaction using logistic regression. Results: Of 630 participants with complete cartilage scores, 280 (44%) were women, mean (standard deviation) age was 49 (13) years, and BMI was 27.3 (4.4) kg/m<sup>2</sup>. KOOS<sub>4</sub> scores at baseline were slightly lower in all lesion groups compared to the no lesion group, yet only the combined group was statistically significantly lower. KOOS<sub>4</sub> trajectories were similar across cartilage lesion patterns, but by final follow-up, adjusted mean KOOS<sub>4</sub> scores were 6.8 (95% CI 2.2, 11.4) to 9.8 (1.1, 18.5) points lower in groups with cartilage lesions compared to the no lesion group. Probability of patient-reported satisfaction did not differ statistically by group. Conclusions: Though KOOS<sub>4</sub> scores were slightly lower in groups with arthroscopically assessed cartilage lesions compared to the no lesion group, trajectories were similar across all groups.</p>

doi.org/10.1016/j.joca.2021.06.002, hdl.handle.net/1765/135958
Osteoarthritis and Cartilage
Erasmus MC: University Medical Center Rotterdam

E.M. (Erin) Macri, A. G. Culvenor, Martin Englund, K. Pihl, C. Varnum, B R Knudsen, … J. B. Thorlund. (2021). Importance of patellofemoral and tibiofemoral cartilage lesions on trajectory of self-reported outcomes in patients at high risk of knee OA. Osteoarthritis and Cartilage, 29(9), 1291–1295. doi:10.1016/j.joca.2021.06.002