<p>Nerve area and motion in carpal tunnel syndrome (CTS) are currently under investigation in terms of prognostic potential. Therefore, there is increasing interest in non-invasive measurement of the nerve using ultrasound. Manual segmentation is time consuming and subject to inter-rater variation, providing an opportunity for automation. Dynamic ultrasound images (n = 5560) of carpal tunnels from 99 clinically diagnosed CTS patients were used to train a U-Net-shaped neural network. The best results from the U-Net were achieved with a location primer as initial region of interest for the segmentations during finger flexion (Dice coefficient = 0.88). This is comparable to the manual Dice measure of 0.92 and higher than the resulting automated Dice measure of wrist flexion (0.81). Although there is a dependency on image quality, a trained U-Net can reliably be used in the assessment of ultrasound-acquired median nerve size and mobility, considerably decreasing manual effort.</p>

doi.org/10.1016/j.ultrasmedbio.2021.03.018, hdl.handle.net/1765/136251
Ultrasound in Medicine and Biology
Erasmus MC: University Medical Center Rotterdam

Raymond T. Festen, V J M M (Verena) Schrier, & Peter C. Amadio. (2021). Automated Segmentation of the Median Nerve in the Carpal Tunnel using U-Net. Ultrasound in Medicine and Biology, 47(7), 1964–1969. doi:10.1016/j.ultrasmedbio.2021.03.018