The main mechanisms by which Campylobacter jejuni causes diarrhea are unknown. In contrast to a recent communication, we report here the absence of an association with the plasmid pVir in patients infected with C. jejuni who developed bloody diarrhea in The Netherlands, and we suggest a role for other virulence determinants.

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Journal of Clinical Microbiology
Erasmus MC: University Medical Center Rotterdam

Louwen, R., van Belkum, A., Wagenaar, J., Doorduyn, Y., Achterberg, R., & Endtz, H. (2006). Lack of association between the presence of the pVir plasmid and bloody diarrhea in Campylobacter jejuni enteritis. Journal of Clinical Microbiology, 44(5), 1867–1868. doi:10.1128/JCM.44.5.1867-1868.2006