The main mechanisms by which Campylobacter jejuni causes diarrhea are unknown. In contrast to a recent communication, we report here the absence of an association with the plasmid pVir in patients infected with C. jejuni who developed bloody diarrhea in The Netherlands, and we suggest a role for other virulence determinants.

Campylobacter Infections/epidemiology/*microbiology, Campylobacter jejuni/*genetics/isolation & purification/pathogenicity, Diarrhea/microbiology, Enteritis/*microbiology, Epidemiology, Molecular, Gastrointestinal Hemorrhage/microbiology, Genes, Bacterial, Humans, Netherlands/epidemiology, Plasmids/genetics/isolation & purification, Virulence/genetics,
Journal of Clinical Microbiology
Erasmus MC: University Medical Center Rotterdam

Louwen, R.P.L, van Belkum, A.F, Wagenaar, J.A, Doorduyn, Y, Achterberg, R, & Endtz, H.P. (2006). Lack of association between the presence of the pVir plasmid and bloody diarrhea in Campylobacter jejuni enteritis. Journal of Clinical Microbiology, 44(5), 1867–1868. doi:10.1128/JCM.44.5.1867-1868.2006