2009-01-27
The spliceosome as target for anticancer treatment
Publication
Publication
British Journal of Cancer , Volume 100 - Issue 2 p. 228- 232
The spliceosome is a ribonucleoprotein complex involved in RNA splicing, that is, the removal of non-coding introns from precursor messenger RNA. (Alternative) Splicing events may play an essential role in tumourigenesis. The recent discovery that the spliceosome is a target for novel compounds with anticancer activity opens up new therapeutic avenues.British Journal of Cancer advance online publication, 25 November 2008; doi:10.1038/sj.bjc.6604801 www.bjcancer.com.
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| doi.org/10.1038/sj.bjc.6604801, hdl.handle.net/1765/14194 | |
| British Journal of Cancer | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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van Alphen, R., Wiemer, E., Burger, H., & Eskens, F. (2009). The spliceosome as target for anticancer treatment. British Journal of Cancer (Vol. 100, pp. 228–232). doi:10.1038/sj.bjc.6604801 |
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