Background: It is unclear whether 16-detector row CT angiography (CTA) can replace digital subtraction angiography (DSA) to assess the feasibility of endovascular treatment (EVT) in the acute phase after aneurysmal subarachnoid hemorrhage. Methods: We studied 80 consecutive patients with aneurysmal subarachnoid hemorrhage, who underwent both CTA and DSA. Two interventional neuroradiologists independently scored CTA and, immediately thereafter, DSA with respect to feasibility of EVT. We determined whether CTA without DSA was sufficient for a definite judgment. We also assessed interobserver agreement. Results: The 2 readers judged EVT to be feasible in 24 and 37 patients with CTA alone and not feasible in 34 and 20 patients. In these patients, DSA yielded additional information in 6 (reader 1) and 5 patients (reader 2), which did not affect treatment decision. In 19 and 7 patients, DSA was considered inferior to CTA. In the remaining patients (n = 22 and 23, respectively), feasibility of EVT could not be judged with CTA alone, and DSA results were required in addition for a treatment decision. Interobserver agreement on feasibility of EVT was just fair (κ <0.40). Conclusions: In our series of patients, 16-detector row CTA was a reliable investigation to assess feasibility of EVT of ruptured intracranial aneurysms in most patients. Further, we found that interobserver disagreement on feasibility of EVT was considerable.

CT angiography, Endovascular treatment, Intracranial aneurysm, Subarachnoid hemorrhage, adult, aged, aneurysm rupture, article, computed tomographic angiography, digital subtraction angiography, female, human, interventional radiology, intracranial aneurysm, major clinical study, male, neuroradiology, priority journal, subarachnoid hemorrhage,
Cerebrovascular Diseases
Erasmus MC: University Medical Center Rotterdam

van der Jagt, M, Flach, H.Z, Tanghe, H.L.J, Bakker, S.L.M, Hunink, M.G.M, Koudstaal, P.J, & van der Lugt, A. (2008). Assessment of feasibility of endovascular treatment of ruptured intracranial aneurysms with 16-detector row CT angiography. Cerebrovascular Diseases, 26(5), 482–488. doi:10.1159/000155985