2009-02-26
Signaling Pathways in Cancer: a Matter of Dosage
Publication
Publication
Signaal transductie in kanker: een kwestie van dosering
The main issue addressed in this thesis is how different levels of signaling activity of the Wnt and TGF-β/BMP pathways can affect transcriptional responses in particular relevant for self-renewal and differentiation both in homeostasis and in cancer. Chapter 1 presents an overview of the existent literature leading to the formulation of the hypothesis that Apc/Wnt pathway acts in a dosage-dependent manner both in normal and neoplastic tissues.
| Additional Metadata | |
|---|---|
| , , , , , | |
| Dutch Cancer Society (KWF),Netherlands Organization for Scientifi c Research (NWO),BSIK Innovation programme “Stem Cells in Development and Disease” (SCDD, BSIK 03038),EUFP6 Migrating Cancer Stem Cells program (MCSCs),Association for International Cancer Research (AICR),Erasmus MC,Josephine Nefkens Institute. | |
| R. Fodde (Riccardo) | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/14964 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Gaspar, C. (2009, February 26). Signaling Pathways in Cancer: a Matter of Dosage. Retrieved from http://hdl.handle.net/1765/14964 |
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| Additional Files | |
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| Gaspar, Claudia Sofia Stellingen (1).pdf , 65kb | |
| 2882_Gaspar, Claudia Sofia Cardoso.jpg Cover Image , 16kb | |
