5, 10 methylenetetrahydrofolate reductase (FADH2), DNA polymorphism, acute lymphoblastic leukemia, article, cancer chemotherapy, child, childhood leukemia, clinical protocol, continuous infusion, controlled study, cytarabine, data analysis, drug megadose, folate metabolism, folic acid, folinic acid, genotype, glycine hydroxymethyltransferase, human, infection, liver toxicity, major clinical study, methionine synthase, methotrexate, methylenetetrahydrofolate dehydrogenase, mucosa inflammation, multiple cycle treatment, patient coding, prednisolone, priority journal, reduced folate carrier, repeated drug dose, retrospective study, side effect, skin toxicity
dx.doi.org/10.1038/leu.2008.66, hdl.handle.net/1765/15146
Erasmus MC: University Medical Center Rotterdam

Huang, L, Tissing, W.J.E, de Jonge, R, van Zelst, B.D, & Pieters, R. (2008). Polymorphisms in folate-related genes: Association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia. Leukemia, 22(9), 1798–1800. doi:10.1038/leu.2008.66