Do synovial biopsies help to support evidence for involvement of innate immunity in the immunopathology of Behçet's disease?
Behçet's disease is a complex vasculitis of unknown etiology. Abundant neutrophils suggest the involvement of innate immunity. Cytokines are skewed to the T-helper-1 pattern. Few sterile organs are easily accessible for analysis in Behçet's disease. Cañete and coworkers identify inflamed joints as a feasible model and suggest the involvement of innate immunity in Behçet's disease.
|Keywords||Behcet disease, arthritis, biopsy, cytokine release, editorial, helper cell, human, immunology, immunopathogenesis, immunopathology, inflammatory cell, innate immunity, joint biopsy, neutrophil, note, psoriatic arthritis, rheumatoid arthritis, signal transduction, synovium|
|Persistent URL||dx.doi.org/10.1186/ar2657, hdl.handle.net/1765/16397|
|Journal||Arthritis Research & Therapy|
van Laar, J.A.M, Kappen, J.H, van Daele, P.L.A, & van Hagen, P.M. (2009). Do synovial biopsies help to support evidence for involvement of innate immunity in the immunopathology of Behçet's disease?. Arthritis Research & Therapy, 11(2). doi:10.1186/ar2657