Behçet's disease is a complex vasculitis of unknown etiology. Abundant neutrophils suggest the involvement of innate immunity. Cytokines are skewed to the T-helper-1 pattern. Few sterile organs are easily accessible for analysis in Behçet's disease. Cañete and coworkers identify inflamed joints as a feasible model and suggest the involvement of innate immunity in Behçet's disease.

Additional Metadata
Keywords Behcet disease, arthritis, biopsy, cytokine release, editorial, helper cell, human, immunology, immunopathogenesis, immunopathology, inflammatory cell, innate immunity, joint biopsy, neutrophil, note, psoriatic arthritis, rheumatoid arthritis, signal transduction, synovium
Persistent URL dx.doi.org/10.1186/ar2657, hdl.handle.net/1765/16397
Journal Arthritis Research & Therapy
Citation
van Laar, J.A.M, Kappen, J.H, van Daele, P.L.A, & van Hagen, P.M. (2009). Do synovial biopsies help to support evidence for involvement of innate immunity in the immunopathology of Behçet's disease?. Arthritis Research & Therapy, 11(2). doi:10.1186/ar2657