2009-10-26
Immunotherapy: Vaccine trials in melanoma -- time for reflection.
Publication
Publication
Nature Reviews Clinical Oncology , Volume 6 - Issue 5 p. 256- 258
The disappointing results of the large, randomized, controlled trials showing no benefit of vaccines in patients with advanced and metastatic melanoma call for a reassessment of the development of therapeutic vaccines and the importance of better immune monitoring methodology, such as adoptive T-cell therapy with lymphodepletion.
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doi.org/10.1038/nrclinonc.2009.42, hdl.handle.net/1765/16741 | |
Nature Reviews Clinical Oncology | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Eggermont, A. (2009). Immunotherapy: Vaccine trials in melanoma -- time for reflection. Nature Reviews Clinical Oncology, 6(5), 256–258. doi:10.1038/nrclinonc.2009.42 |