Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

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Journal Eukaryotic Cell (Print)
Grinsven, K.W.A, van den Abbeele, J, van den Bossche, P, van Hellemond, J.J, & Tielens, A.G.M. (2009). Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms. Eukaryotic Cell (Print), 8(8), 1307–1311. doi:10.1128/EC.00091-09