1998-12-17
(Pro)Renin Uptake and Prorenin Activation in the Cardiovascular System
Publication
Publication
(Pro)renine opname en prorenine activatie in het cardiovasculaire systeem
Traditionally the renin-angiotensin system (RAS) has been viewed as a circulating system. Circulating renin, released by the kidneys, cleaves liver-derived angiotensinogen, which yields the inactive decapeptide angiotensin I (Ang (1-10) or Ang I) (Figure 1). Ang I is subsequently converted into an octapeptide, angiotensin II (Ang (1-8) or Ang II), by angiotensin-converting enzyme (ACE), an enzyme that is either located at the huninal side of the endothelium or circulating freely in plasma. Ang II is rapidly metabolized by so-called angiotensinases.
| Additional Metadata | |
|---|---|
| , , | |
| Netherlands Heart Foundation,Dr Saal van Zwanenberg Foundation | |
| P.R. Saxena (Pramod Ranjan) , M.A.D.H. Schalekamp (Maarten) | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/17193 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
|
van Kesteren, T. (1998, December 17). (Pro)Renin Uptake and Prorenin Activation in the Cardiovascular System. Retrieved from http://hdl.handle.net/1765/17193 |
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| Additional Files | |
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| stellingen kesteren.pdf , 25kb | |
| 1485_KESTEREN-Catharina-Anna-Maria-van.jpg Cover Image , 31kb | |
