Objective: To determine whether pulmonary function at discharge from inpatient rehabilitation can predict respiratory infection in spinal cord injury in the first year after discharge, and to determine which pulmonary function parameter predicts best. Design: Multicentre prospective cohort study. Subjects: A total of 140 persons with spinal cord injury. Methods: Pulmonary function was tested at discharge from inpatient rehabilitation. Pulmonary function parameters (expressed in absolute and percentage predicted values) were: forced vital capacity, forced expiratory volume in 1 sec, and peak expiratory flow. Respiratory infection was determined one year after discharge by a physician. Differences between the respiratory infection and non-respiratory infection groups were tested; and receiver operating characteristic curves were used to determine how accurately pulmonary function parameters could predict respiratory infection. Results: Of the 140 participants, 14 (10%) experienced respiratory infection in the first year after discharge. All pulmonary function parameters were significantly lower in persons who experienced respiratory infection than in those who did not. All pulmonary function parameters were almost equally accurate in predicting respiratory infection; only percentage predicted forced vital capacity was less accurate. Conclusion: Pulmonary function at discharge from inpatient rehabilitation can be used as a predictor of respiratory infection in the first year after discharge in spinal cord injury. No single pulmonary function parameter was a clearly superior predictor of respiratory infection.

Complications, Pulmonary function test, Rehabilitation, Respiratory infections, Sensitivity and specificity, Spinal cord injury, adult, article, clinical trial, cohort analysis, conference paper, female, forced expiratory volume, hospital discharge, human, lung, lung function test, major clinical study, male, middle aged, multicenter study, pathophysiology, peak expiratory flow, physician, prediction, prognosis, prospective study, pulmonary rehabilitation, respiratory tract infection, risk factor, sensitivity and specificity, spinal cord injury, time
dx.doi.org/10.2340/16501977-0410, hdl.handle.net/1765/17542
Journal of Rehabilitation Medicine
Erasmus MC: University Medical Center Rotterdam

Postma, K, Bussmann, J.B.J, Haisma, J.A, van der Woude, L.H, Bergen, M.P, & Stam, H.J. (2009). Predicting respiratory infection one year after inpatient rehabilitation with pulmonary function measured at discharge in persons with spinal cord injury. In Journal of Rehabilitation Medicine (Vol. 41, pp. 729–733). doi:10.2340/16501977-0410